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Science  10 Apr 2015:
Vol. 348, Issue 6231, pp. 246
DOI: 10.1126/science.348.6231.246-a

Three-Position Stage

The Three Position Stage for the VIAFLO 96 and VIAFLO 384 handheld benchtop pipettes expands available stage positions for microplates, reservoirs, and tips on a VIAFLO 96 or VIAFLO 384 from two to three thereby enhancing workflow in a wide range of applications. The Three Position Stage also features an indexing function to allow access to 384-well plates using a 96-channel pipetting head. For plate replication applications, having a tip rack in the left position, the source plate in the middle position, and the target plates in the right position of the Three Position Stage enables the user to replicate the source plate with minimal plate handling effort. Changing tips and target plates can be done without moving the source plate, eliminating the risk of spills. When undertaking compound dilutions or screening, the Three Position Stage enables accurate and rapid addition of reagent and compounds from two different sources (reservoir and plate) to one target screening plate.

GoldNanoparticles

Highly monodisperse, premium Gold NanoRods and Gold NanoSpheres, available in a range of different sizes and peak absorption wavelengths, are ideal for use in imaging, tumor targeting, microscopy, lateral flow assays, SERS, and several other applications. The monodispersity and minimal batch to batch variations ensure superior data quality and consistency. Detailed technical specifications are included with every product to guarantee complete transparency in surface chemistry for researchers performing their own functionalizations and conjugations. Surface coating options include a specialized silica coating in addition to commonly used coatings such as citrate, CTAB, and PEG. The silica coating provides colloidal stability, bioconjugation potential and enhanced optical properties. Silica-coated Gold NanoRods resist melting and shape distortion even when subjected to extreme heat via focused laser beams. In addition to providing thermodynamic stability, the silica-coating also facilitates better heat transfer to the surrounding fluid, thus dramatically increasing imaging signal strength.

Laboratory Information Management System

The Genologics Clarity laboratory information management system (LIMS) has been integrated into the Illumina HiSeq-based workflows to offer next generation sequencing with the highest level of data management and methods control. RNA sequencing, target capture, whole-genome sequencing, and premade library samples are tracked by the LIMS from acquisition through QC, library prep, and Illumina sequencing. Reliable and flexible sample handling is provided for all workflows and chain of custody information is preserved. The Beckman Coulter Life Sciences' Biomek FX liquid handling and robotics platforms are integrated with the system as well, providing further sample processing and security benefits. Any number of robots and QC instruments can be brought into the process and run together, so projects can be scaled as needed. Clarity is one of the few LIMS systems that offer an upgrade option to audit to clinical standards and is approved for CFR part 11 recordkeeping.

Antibodies

Two new product families, QPrEST for mass spectrometry-based protein quantification and PrEST Antigens have been designed to be used as controls in antibody assays. QPrEST represents a new category of isotope-labeled internal mass spectrometry standards, offering distinct advantages over existing products for relative and absolute protein quantification. The initial catalogue contains more than 19,000 QPrESTs targeting 13,000 human proteins. QPrEST improves the standard workflow for mass spectrometry-based proteomics. PrEST Antigens are the recombinant protein fragments used as immunogens in the generation of Triple A Polyclonals. They should be used together with the corresponding antibody for preadsorption assays, or as controls in Western blots, enzyme-linked immunosorbent assays, and protein array assays. This launch includes more than 17,000 PrEST Antigens originally used for generation of the Triple A Polyclonals and PrecisA Monoclonals.

Flexi-Block Accessory

The new Flexi-block accessory can heat almost any sample from ambient temperature up to 200° including those stored in 0.2 mL, 0.5 mL, 2.0 mL, and 5.0 mL micro tubes and any diameter test-tube, vial, cuvette, or microplate. This flexibility means laboratories can achieve new levels of efficiency, as researchers are able to heat any sample, regardless of container or type, without having to change or recalibrate instruments. The Flexi-block's broad range is made possible by the incorporation of 1.5 mL diameter autoclaveable beads. Manufactured from high density ceramic, these exhibit high mechanical strength and are an excellent thermal transfer medium. This outstanding flexibility eliminates the traditional limitation of aluminium heating blocks—their specificity to a particular type of tube, multiwell plate, or glass vial. Flexi-block is unique, economically priced, and comes in two variations: double-width or a larger triple-width version for high throughput heating and incubating applications as well as sensitive analytical procedures.

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  • Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

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