In DepthInfectious Diseases

Ebola survivors fight back in plasma studies

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Science  15 May 2015:
Vol. 348, Issue 6236, pp. 742-743
DOI: 10.1126/science.348.6236.742

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In the Guinean capital, Conakry, 90 people have so far been treated in a clinical trial that aims to seek whether plasma from Ebola survivors can help patients. Animal studies of similar therapies had yielded mixed results, and the findings of a small human study in 1995 were ambiguous. The study aims to recruit 130 patients, but enrollment has ground to a halt because the last Ebola patient in Conakry was discharged on 28 April. Results are expected later this year, but researchers acknowledge that they will be difficult to interpret because the study has no control arm.

  • * in Conakry