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Science  15 May 2015:
Vol. 348, Issue 6236, pp. 822
DOI: 10.1126/science.348.6236.822-a

96-Well Deep Well Plate

The new low-profile 96-well deep well plates achieve a storage volume of 1.1 mL/well in a height of just 27 mm enabling more plates to be stacked or stored in a given space. Manufactured from extractables-free polypropylene in an ISO 10,000 approved clean room environment, Porvair low-profile plates undergo extensive quality testing to ensure they are of the highest quality, certified free from DNase, RNase, and endotoxin contamination. Combining an affordable price with uncompromising high quality, Porvair low-profile 96-well deep well plates are precisely manufactured to comply with ANSI/SLAS dimensional standards ensuring complete compatibility with all automated sample handling systems, microplate readers, and washers. Complementing the low-profile plate, Porvair also offers a matching anti-evaporation cap mat, manufactured from thermoplastic elastomer, to ensure the long-term integrity of your stored samples.

Neural Transfection Reagent

The DNA-In Neuro is a new generation transfection reagent developed specifically for maximum nucleic acid delivery into neurons, typically achieving a twofold or greater improvement in efficiency over currently available competing reagents. Neurons are among the most difficult cell types to transfect. DNA-In Neuro Transfection Reagent offers researchers a cost- effective, robust and easy-to-use DNA delivery solution for transfecting freshly isolated and cryopreserved neurons. DNA-In Neuro Transfection Reagent reproducibly transfects neurons and neural stem cells at optimal efficiency with exceptionally low toxicity to support uncompromised post-transfection assays. Comprising a proprietary formulation of chemically defined compounds, DNA-In Neuro Transfection Reagent is completely free of animal-derived components. Designed for use with a quick and easy to follow, single-tube reagent protocol, DNA-In Neuro Transfection Reagent produces great results on the very first try.

Xeno-Free and Serum-Free Medium

PRIME-XV T Cell Expansion XSFM is a xeno-free and serum-free medium optimized for the expansion of human T cells that reliably maintains potency and is the newest medium in the PRIME-XV cell therapy product line that supports immunotherapy. Immunotherapy has emerged as a viable approach for treating some forms of cancer. Using a process called adoptive cell transfer (ACT), T cells have been engineered to produce chimeric antigen receptors (CARs), a surface receptor that allows T cells to recognize tumor-specific proteins and subsequently kill the targeted tumor cells. This method has generated positive results in small clinical trials, indicating its potential as a treatment. To further support the research and development into ACT, efficient expansion of desired T cell subsets with proper potency is critical to ensure an adequate population of T cells with targeted specificity. To facilitate clinical applications and scale-up, PRIME-XV T Cell Expansion XSFM is available for custom formulation and packaging.

HPLC/UHPLC Columns

The Kinetex F5 is a robust pentafluorophenyl propyl (PFP) core-shell phase that overcomes reproducibility and performance limitations of existing PFP and F5 products on the market. The new Kinetex F5 phase delivers improved reproducibility compared to other PFP or F5 columns and can significantly reduce method development time with its dynamic and responsive chemical functionality. It is an ideal solution for high- and ultrahigh-performance liquid chromatography (HPLC/UHPLC) development work with its combination of polar and nonpolar interactions including hydrogen bonding, electrostatic, hydrophobic, aromatic, and steric/planar mechanisms. Additional versatility of this phase gives scientists the ability to use reversed phase, 2D-LC, HILIC, SFC, or even 100% aqueous separation modes. With its fluorinated groups and carbon ring structure, the Kinetex F5 is an excellent choice for both polar and nonpolar compound separations as well as challenging methods that include halogenated, conjugated, or isomeric compounds.

EMCCD Spectroscopy Camera

The new Synapse EM is a deep-cooled EMCCD Scientific camera for low-light and ultrafast spectroscopy experiments. The Synapse EM is available in front and back illuminated for optimal quantum efficiency. With a sensor format of 1,600 x 200 or 1,600 x 400 and a pixel size of 16 &um;m, the Synapse EM is the ideal candidate for high spectral resolution measurements. The camera comes with a standard dual readout mode that allows the users to switch automatically between EMCCD mode for low-light measurements and conventional CCD mode for standard spectroscopy. The SynapseEM comes with several sensor options including the QExtra technology. QExtra technology is available standard in the Synapse EM-BIQX and is an antireflective multilayer coating designed to greatly improve quantum efficiency of back-illuminated sensors over a broad spectral range, while suppressing undesirable etaloning effects. With a maximum frame rate above 1,600 spectra per second and outstanding linearity, the Synapse EM is the ideal EMCCD scientific camera for Raman, SERS/TERS, multitrack, transient, and single molecule spectroscopic applications.

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  • Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

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