Research Article

High burden and pervasive positive selection of somatic mutations in normal human skin

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Science  22 May 2015:
Vol. 348, Issue 6237, pp. 880-886
DOI: 10.1126/science.aaa6806

Article Information

vol. 348 no. 6237 880-886

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History: 
  • Received for publication January 13, 2015
  • Accepted for publication April 13, 2015

Author Information

  1. Iñigo Martincorena1,
  2. Amit Roshan2,
  3. Moritz Gerstung1,
  4. Peter Ellis1,
  5. Peter Van Loo1,3,4,
  6. Stuart McLaren1,
  7. David C. Wedge1,
  8. Anthony Fullam1,
  9. Ludmil B. Alexandrov1,
  10. Jose M. Tubio1,
  11. Lucy Stebbings1,
  12. Andrew Menzies1,
  13. Sara Widaa1,
  14. Michael R. Stratton1,
  15. Philip H. Jones2,*,
  16. Peter J. Campbell1,5,*
  1. 1Wellcome Trust Sanger Institute, Hinxton CB10 1SA, Cambridgeshire, UK.
  2. 2MRC Cancer Unit, Hutchison-MRC Research Centre, University of Cambridge, Cambridge, UK.
  3. 3Francis Crick Institute, London, UK.
  4. 4Department of Human Genetics, University of Leuven, Leuven, Belgium.
  5. 5Department of Haematology, University of Cambridge, Cambridge, UK.
  1. *Corresponding author. E-mail: phj20{at}mrc-cu.cam.ac.uk (P.H.J.); pc8{at}sanger.ac.uk (P.J.C.)

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