Science Webinar Series

Advances in addiction research: Applying genetic biomarkers to personalize treatments

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Science  29 May 2015:
Vol. 348, Issue 6238, pp. 1044
DOI: 10.1126/science.348.6238.1044-c


Advancements in genetics, sequencing technology, and bioinformatics are changing the principles of current medical practice and transforming the standards of patient care. Genetic detection of common and rare variants within populations provides valuable information about predisposition and vulnerability to complex human disease. Data from large-scale genome-wide association studies have identified genetic variations correlated to biological events, enabling combinations of genetic and non-genetic markers to be translated into potential diagnostic tools. However, aspects of these programs are still evolving, including best practices for protocol development, sample processing, genetic/genomic analysis, data management, and quality control. In this webinar, our expert panel will discuss how to better define these procedures and maximize the use of precious, limited clinical samples by utilizing recent innovations, advances in technology, and current best practices.