Books et al.Neuroscience

Facing our fears

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Science  03 Jul 2015:
Vol. 349, Issue 6243, pp. 39
DOI: 10.1126/science.aab3289

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In Anxious, renowned neuroscientist Joseph LeDoux tackles the neural origins of fear and anxiety with an eye to developing empirically informed treatments for anxiety disorders. In a significant departure from his earlier views on the neural underpinnings of fear, LeDoux carves the emotional brain into two parts:  an evolutionarily old threat detection system, centered in the amygdala, and a new system that underlies the conscious feeling of fear, centered in the prefrontal cortex. Though controversial, reviewer Stephen Maren finds LeDoux's arguments compelling, and applauds Anxious as a "novel roadmap for future work in both the laboratory and the clinic."