Science Webinar Series

Generating the best superresolution microscopy data: Finding the right tool for the right job

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Science  24 Jul 2015:
Vol. 349, Issue 6246, pp. 441
DOI: 10.1126/science.349.6246.441-c


Superresolution microscopy has recently been making headlines again, not least because it was the breakthrough that spurred Eric Betzig, Stefan Hell, and William Moerner to be awarded the Nobel Prize for Chemistry in 2014. The number of superresolution technologies keeps increasing, along with an alphabet soup of acronyms that includes SIM, SPIM, STED, PALM, and STORM. It is difficult enough for the microscopy experts to keep up, but even more challenging for the average biologist, particularly when they are looking for more from their data than a standard or confocal microscope can offer. When faced with the array of possible techniques, how does one decide which technique is going to get the results needed for that next major publication? In this webinar we will discuss the newest developments in superresolution microscopy and provide practical advice on obtaining the best imaging results. Our panelists, including 2014 Nobel Prize winner Eric Betzig, will help you find the right tool to answer your biological question. You will also hear case studies about how superresolution microscopy data has made the difference between acceptance and rejection of key papers by scientific journals.