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Science  28 Aug 2015:
Vol. 349, Issue 6251, pp. 999
DOI: 10.1126/science.349.6251.999-a

Conical Tubes

With the introduction of the two 15 mL and 50 mL screw cap tubes, Eppendorf Tubes now cover the entire volume range from 0.5 mL to 50 mL. The newly designed screw caps provide not only optimal sealing properties, but with their grooved and multisurface side-contour, they simultaneously ensure a secure, slip-free grip. The optimized handling features further facilitate safe opening and closing of the tubes via convenient one-handed operation. The Eppendorf Conical Tubes are further characterized by an expanded purity grade: they are not only sterile and pyrogen-free, but they are also free from DNAses and RNAses as well as human and bacterial DNA. These features make them ideally suited for cell biology applications in a sterile environment, which rely on freedom from contaminations with DNA. The highest level of manufacturing precision and robustness ensures smooth performance of these tubes in laboratory instruments such as centrifuges or thermomixers.

Lab Management System

The NuGenesis Lab Management System is a unique and powerful alternative to a traditional laboratory information management system with advances that enable deeper insight into scientific challenges, accelerated decision-making, better business results, and compliance with government regulations. The NuGenesis Lab Management System offers high-impact functionality. New advances include NuGenesis SampleShare, an optional, secure webclient for sample submissions and results management; NuGenesis Stability, a complete stability protocol management and testing solution to facilitate a consistent regimented workflow across lab operations; NuGenesis Connectors, a bidirectional link between lab systems and business applications; and Paradigm Scientific Search, a fully integrated scientific search solution for text, documents, and science objects. Uniquely combining data, workflow, and sample management capabilities to support the entire product lifecycle from discovery through manufacturing, the NuGenesis Lab Management System is a user-centric platform that encompasses a scientific data management system, electronic laboratory notebook, and laboratory execution system.

SFE Bio-Botanical Extraction System

A new 10 L extraction vessel is now available for the SFE Bio-Botanical Extraction System (BBES), a multivessel supercritical fluid extraction (SFE) system that rapidly fractionates and extracts large quantities of desired components from a multitude of botanical matrices. The BBES functions as a bulk-scale, high-pressure separator for collecting extracted compounds. The 10 L vessel doubles current capacity and can be acquired as an add-on to installed systems. Furthermore, a new computer-controlled automation module that allows the SFE BBES to extract the high-quality product in less time with even less manual intervention is expected to be available soon. The new automation module will provide greater flexibility for unattended operation through seamless transition between the first and second extractions without user intervention, thereby extending uninterrupted operation even further. The SFE BBES uses supercritical CO2 as its mobile phase, which has been shown to be a safer alternative to organic solvents or hydrocarbons (butane).

Heat-Stabilization System

The Denator Stabilizor heat-stabilization system preserves lipids at close to in vivo levels. To preserve lipids in a reliable manner prior to mass spectrometry- based analysis is pivotal to accurately quantify and identify potential biomarkers and perform disease research. Lipids play several key roles in biological systems including storing energy, cell signaling, and acting as components of cell membranes. However, it is often difficult to quantify accurate levels of lipids in tissue samples due to post-sampling changes that cause substantial variations in detected lipid levels during sample preparation. Denator's Stabilizor system has been shown to stop degradation and other post-sampling changes immediately and permanently. This ensures a stable sample from the moment of excision until the point of analysis, which increases the accuracy and quality of analytical results. By using heat stabilization, scientists are able to drastically improve the consistency of sample quality and discover new, biologically relevant information without needing to use inhibitors.

Xeno-Free and Endotoxin-Free Human Cytokines

A complete new range of commonly used human cytokines and growth factors is now available. Unlike most other commercially available cytokine products, ActiveMax cytokines are expressed exclusively in human cells under strict animal-free and xeno-free conditions. Therefore, they are uniquely suitable for human cell culture and assay development. Endotoxin and other nonhuman components can provoke an immune response in human systems. These contaminations are significant complicating factors for human cell culture experiments, in particular those relevant to human cell therapy or other clinical applications. ActiveMax cytokines are exclusively produced in a serum-free, animal component-free, and chemically defined cell culture system. These cytokines are absolutely xeno-free, and have an endotoxin level of less than 1.0 Ehrlich unit per microgram. The bulk production of ActiveMax cytokines relies entirely on the human cellular machinery provided by the HEK293 cells, and therefore retains their authentic posttranslational processing, which translates into high bioactivity and stability.

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  • Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

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