Science Webinar Series

Characterizing cell morphology using imaging flow cytometry

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Science  28 Aug 2015:
Vol. 349, Issue 6251, pp. 999
DOI: 10.1126/science.349.6251.999-c


Defining the morphological characteristics—such as the size, shape, or structure—of different cell types has played a key role in assessing the progression and status of various diseases. Imaging flow cytometry combines the visual analysis capabilities of microscopy with flow cytometry to provide researchers with a powerful tool to study cell morphology and the potential effects of therapeutic interventions. In this webinar, we will explore ways to characterize cell morphology and how this information can be applied to better understand blood disorders, including how erythrocyte morphology is used in the analysis of sickle cell disease and to identify functional intermediates in erythropoiesis.