Science Webinar Series

Advancing precision medicine through multi-omics: An integrated approach to tumor profiling

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Science  11 Sep 2015:
Vol. 349, Issue 6253, pp. 1246
DOI: 10.1126/science.349.6253.1246-c

Summary

While technological breakthroughs of the last decade have greatly advanced our understanding of the cancer genome, they have also revealed the immense complexity and heterogeneity of tumors. The key to further advancing our understanding and treatment of cancer is to distinguish between genes and pathways that drive tumorigenesis (driver events) and neutral, passenger events. A growing body of evidence has shown that not all DNA-level alterations have biological implications, making it necessary to examine multiple ꞌomics levels including the transcriptome and proteome, to identify critical driver events. In this webinar, our expert panel will discuss how using a multi-omics–based approach to cancer research can advance our understanding of cancer biology as well as lead to the discovery of novel biomarkers.