Technical Comments

Response to Comment on “Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism”

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Science  30 Oct 2015:
Vol. 350, Issue 6260, pp. 519
DOI: 10.1126/science.aab2595

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Wang comments that the diffraction data for the structure of the A139T mutant of translocator protein TSPO from Rhodobacter sphaeroides should be used to 1.65 instead of 1.8 angstroms and that the density interpreted as porphyrin and monoolein is better fitted as polyethylene glycol. Although different practices of data processing exist, in this case they do not substantially influence the final map. Additional data are presented supporting the fit of a porphyrin and monooleins.

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