In DepthOncology

Vitamin C could target some common cancers

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Science  06 Nov 2015:
Vol. 350, Issue 6261, pp. 619
DOI: 10.1126/science.350.6261.619

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Decades ago, Nobel Prize–winning chemist Linus Pauling was relegated to the fringes of medicine after championing the idea that vitamin C could combat a host of medical conditions, including cancer. Now, a study published online this week by Science reports that vitamin C can kill tumor cells that carry a common cancer-causing mutation and, in mice, can curb the growth of tumors with the mutation. If the findings hold up in people, researchers may have found a way to treat a large swath of tumors that have lacked effective drugs. Because high dose vitamin C is already known to be safe, clinical trials to test this idea could move ahead quickly.