PerspectiveRetrospective

Alan Hall (1952–2015)

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Science  27 Nov 2015:
Vol. 350, Issue 6264, pp. 1039
DOI: 10.1126/science.aad8407

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Summary

Alan Hall, a remarkable cell and cancer biologist, died suddenly on 3 May in New York City. He was an outstanding researcher, teacher, and colleague. In the 1980s, in his early career, Alan was one of a small group of molecular biologists who first revealed how genetic changes could cause cancer. Alan and his colleagues undertook pioneering work that revealed the mechanisms through which the Rho family of small guanosine triphosphatases (GTPases) regulate the cytoskeleton and thus how cells control their shapes and movement. He became one of the world's leading cell biologists and was a committed mentor to generations of young scientists.