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Science  11 Dec 2015:
Vol. 350, Issue 6266, pp. 1397
DOI: 10.1126/science.350.6266.1397-a

Gel Documentation System

The HeroDoc Plus is a compact gel documentation system for imaging gels and blots. The compact darkroom/hood assembly will sit comfortably on any laboratory bench within its small footprint. A unique lift-up hood and a built-in ultraviolet (UV) protection shield enable the user to do preparative work easily and safely. Should the user wish to raise the shield, an automatic cutoff switch will protect the user from any harmful effects of UV light. A high sensitivity, charge-coupled device (CCD) camera combined with a distortion-free, software-controlled lens ensures quality image capture from 10 milliseconds up to 60 minutes. This is more than adequate for most fluorescent gel and blot image capture. Illumination comes from a massive 28 cm × 22 cm filter midrange transilluminator, while built-in white and blue light light-emitting diodes (LEDs) provide epi-illumination as standard. Multilanguage, HeroStore image capture and control software effortlessly enables the user to acquire images of gels and blots.

Liquid Chromatography System

Proteomics laboratories can benefit from the new nano LC system with dedicated columns as front-end for liquid chromatography mass spectrometry (LC-MS). The EASY-nLC 1200 system provides effortless separation performance and high-throughput capacity and is designed for robust and reliable operation at 1200 bar. New maintenance-free ceramic valves decrease system downtime, and tool-free nanoViper connections provide fast and reproducible fluidic connections over the complete flow path. New software features enhance performance and usability, simplifying operation and maintenance and offering users at various levels of expertise a fully integrated solution that consistently generates high-quality data. The new Acclaim PepMap nano LC columns are designed to handle the 1200 bar-pressure capability of the EASY-nLC 1200. In particular, the new 75 cm format provides high peak capacity intended to increase sensitivity and resolution.

Gel Imager

The Imagel Gel Doc system for iPhone or Android is the smart way to quickly grab your gel images. Just hook up your smartphone to the compact hood and start to collect images of all your gels quickly and easily. The Imagel can be used with three different light sources. Use the blue light-emitting diode (LED) transilluminator for DNA applications that use Green DNA, GelGren, SYBR Green, SYBR Safe, SYBR Gold, and for protein applications using LavaPurple. An ultraviolet transilluminator will let you work with AmberDNA, ethidium bromide, SYBR, Oriole, fluorescent gel stain, GelRed, SYPRO Ruby, Coomassie, Fluor Orange, and Krypton. Also, using a white light source you can capture images of proteins using Coomassie Blue, copper, silver, or zinc stains. The Imagel is very simple to use—just snap a photo and save on your phone or upload to the cloud for hosting, sharing, and image analysis and annotation features.

ChIP-Validated Antibodies

ChIP-validated antibodies further enhance the high-performance application solutions that Chromatrap can provide researchers. The use of high-quality and specific chromatin immunoprecipitation (ChIP)-validated antibodies is essential for the success of a ChIP assay. The antibody must recognize and bind to native protein that is bound to DNA. Antibodies from other applications do not always work well in ChIP. These top-quality validated antibodies are now offered alongside the expanding range of kits for ChIP assays of every type. Chromatrap currently offers a range of ChIP kits for quantitative polymerase chain reaction (qPCR) or sequencing and has now launched the first nine antibodies in its validated antibody program, which are H3, RNA pol II (S), RNA pol II (S5), H3K9me3, 5mC, AcH3, AcH4, AR, and Sin3a. Chromatrap validated antibodies are available in 100 uL aliquots at a concentration of 1 mg/ml.

Imaging System

The Omega Lum W analysis system can be used for gel, multicolor R, G, B, and chemiluminescent imaging. This compact package sits neatly on any laboratory bench ready to image gels, Western blots, or multiplexing multicolored blots at the click of a button. At the heart of any gel documentation system is a quality camera, and the Omega Lum W comes with one of the best. A massive 8.4 megapixel, scientific grade, cooled charge-coupled device (CCD) camera combined with an f/0.95 motorized lens and six-position filter wheel gives the system outstanding power and performance. This combination provides the highest sensitivity and signal capture for perfect imaging, giving amazingly low background and a wide dynamic range for accurate quantification. One of the system's key features is the SmartCapture Technology. This unique automated control eliminates the need for filter selection and focus adjustment, thereby helping the user to obtain high-quality images every time.

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  • Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

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