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Runners-up

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Science  18 Dec 2015:
Vol. 350, Issue 6267, pp. 1458-1463
DOI: 10.1126/science.350.6267.1458

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Summary

In addition to the Breakthrough of the Year, Science listed nine unranked finalists as runners-up. They include missions to the dwarf planets Pluto and Ceres, studies of the DNA of Kennewick Man, efforts to make psychology research more reproducible, the discovery of fossils of a new human species in a South African cave, confirmation of the existence of deep plumes of hot rock rising from the bottom of Earth's mantle, an effective vaccine against Ebola, the surprising discovery that the body's lymph vessels extend to the central nervous system, engineered yeast that produce painkilling opioids, and a loophole-free experiment that showed that a weird quantum phenomenon called entanglement can act instantaneously over large distances.