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Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder

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Science  22 Jan 2016:
Vol. 351, Issue 6271, pp. 397-400
DOI: 10.1126/science.aad7977

Article Information

vol. 351 no. 6271 397-400

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History: 
  • Received for publication November 4, 2015
  • Accepted for publication December 11, 2015

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Author Information

  1. Qi Chen1,3,*,,
  2. Menghong Yan2,,
  3. Zhonghong Cao1,5,,
  4. Xin Li1,,
  5. Yunfang Zhang1,5,,
  6. Junchao Shi1,5,,
  7. Gui-hai Feng1,
  8. Hongying Peng1,4,
  9. Xudong Zhang1,5,
  10. Ying Zhang1,
  11. Jingjing Qian1,5,
  12. Enkui Duan1,*,
  13. Qiwei Zhai2,*,
  14. Qi Zhou1,*
  1. 1State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
  2. 2Key Laboratory of Nutrition and Metabolism, Chinese Academy of Sciences Center for Excellence in Molecular Cell Science, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.
  3. 3Department of Physiology and Cell Biology, School of Medicine, University of Nevada, Reno, NV 89512 USA.
  4. 4Beijing Royal Integrative Medicine Hospital, Beijing University of Chinese Medicine, Beijing, China.
  5. 5University of Chinese Academy of Sciences, Beijing 100049, China.
  1. *Corresponding author. E-mail: cqi{at}medicine.nevada.edu (Q.C.); duane{at}ioz.ac.cn (E.D.); qwzhai{at}sibs.ac.cn (Q.Zha.); qzhou{at}ioz.ac.cn (Q.Zho.)
  1. These authors contributed equally to this work.

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