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Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy

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Science  22 Jan 2016:
Vol. 351, Issue 6271, pp. 400-403
DOI: 10.1126/science.aad5725

Article Information

vol. 351 no. 6271 400-403

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History: 
  • Received for publication October 2, 2015
  • Accepted for publication December 4, 2015

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Author Information

  1. Chengzu Long1,2,3,*,
  2. Leonela Amoasii1,2,3,*,
  3. Alex A. Mireault1,2,3,
  4. John R. McAnally1,2,3,
  5. Hui Li1,2,3,
  6. Efrain Sanchez-Ortiz1,2,3,
  7. Samadrita Bhattacharyya1,2,3,
  8. John M. Shelton4,
  9. Rhonda Bassel-Duby1,2,3,
  10. Eric N. Olson1,2,3,
  1. 1Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  2. 2Hamon Center for Regenerative Science and Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  3. 3Sen. Paul D. Wellstone Muscular Dystrophy Cooperative Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  4. 4Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  1. Corresponding author. E-mail: eric.olson{at}utsouthwestern.edu
  1. * These authors contributed equally to this work.

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Article usage: December 2015 to November 2017

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Dec 2015315562149
Jan 20162752219673857
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