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Science  29 Jan 2016:
Vol. 351, Issue 6272, pp. 517
DOI: 10.1126/science.351.6272.517

LED Illuminator

X-Cite TURBO is a new multiwavelength light-emitting diode (LED) fluorescence illuminator for microscopy imaging and detection applications. Featuring the patent-pending LaserLED Hybrid Drive, X-Cite TURBO provides maximum excitation power for all standard color wavelengths. The new X-Cite TURBO enables precise control by balancing illumination intensities between six popular wavelengths to protect samples from photodamage. Original equipment manufacturers (OEMs) and microscopists are able to define the exact bandwidth of light desired to reach the fluorophore for maximum excitation efficiency. X-Cite TURBO enables individual or simultaneous excitation of all fluorophores ranging from 4',6-diamidino-2-phenylindole (DAPI) to cyanine 5 (Cy5), or fluorescence proteins from cyan fluorescence protein (CFP) to mCherry, making it suitable for conducting a variety of live or fixed-cell imaging and detection experiments. X-Cite TURBO also features the valuable benefits of LED technology such as long lifetimes, mercury-free operation, virtually zero maintenance, and instant on/off capabilities. Additionally, the intensity of each of the six LEDs can be controlled independently through analog signals or PC control interface.

Antibiotic Sensitivity Testing

The mASTer (measuring antibiotic susceptibility testing easily and rapidly) software saves microbiologists hours of work by reproducibly measuring zones around antibiotic discs on antibiotic susceptibility testing (AST) plates and then automatically producing a bacteria's antibiotic susceptible, intermediate, or resistant (SIR) category. The versatile mASTer software can be used to analyze AST plate images generated by a Synbiosis ProtoCOL 3 automated zone measurement system or by a Syngene G:BOX image analyzer. Using a ProtoCOL 3 system with the new mASTer software allows scientists to work in a high-throughput batch mode to accurately measure zones around antibiotic sensitivity discs. With the G:BOX, microbiologists simply generate monochrome images of their AST plates and import them into the mASTer software. The mASTer software will, at the touch of a button, automatically measure inhibition zones on the true-to-life images and compare the results to data from all the tested microbes that have breakpoint values in the European Committee on Antimicrobial Susceptibility Testing (EUCAST) database.

Ductless Balance Enclosures

Ideal for areas with restricted bench space, the AirClean Systems' popular PowderSafe Type A ductless balance enclosures have been further expanded to include the AC705, a smaller 24-inch wide model. Based on AirClean Systems' proven PowderSafe Type A design, the new AC705 provides operator protection from exposure to harmful powders and particulates, without disturbing balance readings. Each PowderSafe AC705 balance enclosure features an electrostatically-charged prefilter and high-efficiency particulate arrestance (HEPA) filtration for fine particulate capture. A mini-helic air flow gauge, HEPA filter-change indicator light, and integral polypropylene base are also standard. PowderSafe Type A ductless balance enclosures are manufactured in the United States and are shipped fully assembled. The installed HEPA filtration on each enclosure is leak-tested prior to shipment, making it ready for use upon arrival without on-site certification.

Adjustable Rigid Post Mounts

The HZP Series adjustable rigid post mounts provide a simple, flexible, stable, and low-cost solution for electophysiology applications. Compatible with upright and inverted microscopes and available in four different heights, the Prior HZP series is designed to work with Sensapex zero-drift solid state and other common micromanipulators. The HZP series offers a 60° sliding dovetail for smooth, stable positioning and requires no tools for height and rotational adjustment. Compatible with 1/4-20 and 6 mm optical breadboards, the HZP adjustable rigid post mounts are available with a micromanipulator platform, a platform for Prior standard sample holders, or a 110 mm diameter circular sample holder for recording chambers and standard microscope manual stage inserts.

Mutation Enrichment Kits

ICEme Mutation Enrichment Kits allow researchers to supercharge the sequencing platforms already present in their labs, including Sanger, next-generation sequencing (NGS), and droplet digital polymerase chain reaction (ddPCR), and achieve greatly improved detection. The kits leverage the distinctive performance attributes of multiplexed ice cold PCR (MX-ICP) technology to help cancer researchers accelerate the discovery of biomarkers, aid cancer research, and eventually improve cancer patient diagnosis and treatment. The kits work well with virtually any type of patient sample, including tissue, blood, plasma, urine, and other biofluids. MX-ICP technology is also nonallele specific, amplifying all mutations in the region under investigation. It delivers ultrahigh sensitivity, providing up to a 500-fold increase in mutation detection compared to most current methods, with levels of detection routinely achievable down to 0.01%. The kits are easily customizable for use with either single mutations or in combination—researchers can select the mutations they want. The initial menu includes 17 clinically relevant, actionable mutations that are associated with various cancers.

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  • Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

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