Report

mTORC1 induces purine synthesis through control of the mitochondrial tetrahydrofolate cycle

See allHide authors and affiliations

Science  12 Feb 2016:
Vol. 351, Issue 6274, pp. 728-733
DOI: 10.1126/science.aad0489

Article Information

vol. 351 no. 6274 728-733

PubMed: 
Print ISSN: 
Online ISSN: 
History: 
  • Received for publication July 17, 2015
  • Accepted for publication December 11, 2015

Author Information

  1. Issam Ben-Sahra1,*,
  2. Gerta Hoxhaj1,*,
  3. Stéphane J. H. Ricoult1,
  4. John M. Asara2,
  5. Brendan D. Manning1,
  1. 1Department of Genetics and Complex Diseases, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USA.
  2. 2Division of Signal Transduction, Beth Israel Deaconess Medical Center and Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.
  1. Corresponding author. E-mail: bmanning{at}hsph.harvard.edu
  1. * These authors contributed equally to this work.

Altmetric

Article usage

Article usage: February 2016 to June 2018

AbstractFullPdf
Feb 201689868141842
Mar 20161562381698
Apr 2016548133273
May 2016463105207
Jun 201637168140
Jul 201636158104
Aug 201629557110
Sep 201622539123
Oct 201631762168
Nov 201629334102
Dec 20161992475
Jan 20172595487
Feb 20172194489
Mar 201723946121
Apr 20171904674
May 20171624768
Jun 20171514083
Jul 20171473973
Aug 20171342261
Sep 20171052851
Oct 20172346292
Nov 20171824874
Dec 20171873976
Jan 20181523351
Feb 20181513467
Mar 20181873587
Apr 20181763879
May 20182123059
Jun 20181102143