The phenotypic legacy of admixture between modern humans and Neandertals

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Science  12 Feb 2016:
Vol. 351, Issue 6274, pp. 737-741
DOI: 10.1126/science.aad2149

Article Information

vol. 351 no. 6274 737-741

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  • Received for publication August 10, 2015
  • Accepted for publication January 8, 2016

Author Information

  1. Corinne N. Simonti1,
  2. Benjamin Vernot2,
  3. Lisa Bastarache3,
  4. Erwin Bottinger4,
  5. David S. Carrell5,
  6. Rex L. Chisholm6,
  7. David R. Crosslin2,5,
  8. Scott J. Hebbring7,
  9. Gail P. Jarvik2,5,
  10. Iftikhar J. Kullo8,
  11. Rongling Li9,
  12. Jyotishman Pathak10,*,
  13. Marylyn D. Ritchie11,12,
  14. Dan M. Roden1,3,13,14,
  15. Shefali S. Verma11,
  16. Gerard Tromp15,16,
  17. Jeffrey D. Prato3,
  18. William S. Bush17,
  19. Joshua M. Akey2,,
  20. Joshua C. Denny1,3,13,,
  21. John A. Capra1,3,18,19,
  1. 1Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA.
  2. 2Department of Genome Sciences, University of Washington, Seattle, WA, USA.
  3. 3Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA.
  4. 4Mount Sinai School of Medicine, New York, NY, USA.
  5. 5Department of Medicine (Medical Genetics), University of Washington Medical Center, Seattle, WA, USA.
  6. 6Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
  7. 7Center for Human Genetics, Marshfield Clinic, Marshfield, WI, USA.
  8. 8Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA.
  9. 9Division of Genomic Medicine, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA.
  10. 10Division of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
  11. 11Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA, USA.
  12. 12Biomedical and Translational Informatics, Geisinger Health System, Danville, PA, USA.
  13. 13Department of Medicine, Vanderbilt University, Nashville, TN, USA.
  14. 14Department of Pharmacology, Vanderbilt University, Nashville, TN, USA.
  15. 15Weis Center for Research, Geisinger Health System, Danville, PA, USA.
  16. 16Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Health Science, Stellenbosch University, Tygerberg, South Africa.
  17. 17Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH, USA.
  18. 18Department of Biological Sciences, Vanderbilt University, Nashville, TN, USA.
  19. 19Center for Quantitative Sciences, Vanderbilt University, Nashville, TN, USA.
  1. Corresponding author. E-mail: tony.capra{at}
  1. * These authors contributed equally to this work.

  2. Department of Healthcare Policy and Research, Weill Cornell Medical College, New York, NY, USA.


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