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Comment on “Cortical folding scales universally with surface area and thickness, not number of neurons”

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Science  19 Feb 2016:
Vol. 351, Issue 6275, pp. 825
DOI: 10.1126/science.aad0127

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The cerebrum of large mammals is convoluted, whereas that of small mammals is smooth. Mota and Herculano-Houzel (Reports, 3 July 2015, p. 74) inspired a model on an old theory that proposed a fractal geometry. I show that their model reduces to the product of gray-matter proportion times the folding index. This proportional relation describes the available data even better than the fractal model.

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