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Comment on “Cortical folding scales universally with surface area and thickness, not number of neurons”

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Science  19 Feb 2016:
Vol. 351, Issue 6275, pp. 825
DOI: 10.1126/science.aad2029

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Mota and Herculano-Houzel (Reports, 3 July 2015, p. 74) assign power functions to neuroanatomical data and present a model to account for evolutionary patterns of cortical folding in the mammalian brain. We detail how the model assumptions are in conflict with experimental and observational work and show that the model itself does not accurately fit the data.

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