Research Article

On-demand continuous-flow production of pharmaceuticals in a compact, reconfigurable system

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Science  01 Apr 2016:
Vol. 352, Issue 6281, pp. 61-67
DOI: 10.1126/science.aaf1337

Article Information

vol. 352 no. 6281 61-67

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History: 
  • Received for publication December 21, 2015
  • Accepted for publication February 22, 2016

Author Information

  1. Andrea Adamo1,
  2. Rachel L. Beingessner2,
  3. Mohsen Behnam1,*,
  4. Jie Chen1,
  5. Timothy F. Jamison2,,
  6. Klavs F. Jensen1,,
  7. Jean-Christophe M. Monbaliu1,,
  8. Allan S. Myerson1,,
  9. Eve M. Revalor1,§,
  10. David R. Snead2,||,
  11. Torsten Stelzer1,,
  12. Nopphon Weeranoppanant1,
  13. Shin Yee Wong1,#,
  14. Ping Zhang2,**
  1. 1Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
  2. 2Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
  1. Corresponding author. E-mail: tfj{at}mit.edu (T.F.J); kfjensen{at}mit.edu (K.F.J); myerson{at}mit.edu (A.S.M)
  • * Present address: Nuvera Fuel Cells, 129 Concord Road, Billerica, MA 01821, USA.

  • Present address: Department of Chemistry, University of Liège, Quartier Agora, Allée du six Août 13, B-4000 Liège (Sart Tilman), Belgium.

  • § Present address: Department of Chemical and Biomolecular Engineering, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, 3010 VIC, Australia.

  • ||Present address: Georgia-Pacific Chemicals, 2883 Miller Road, Decatur, GA 30312, USA.

  • Present address: Department of Pharmaceutical Sciences, University of Puerto Rico, Medical Sciences Campus, San Juan, PR 00936, USA.

  • # Present address: Chemical Engineering and Food Technology Cluster, Singapore Institute of Technology, 10 Dover Drive, Singapore 138683.

  • ** Present address: Novartis Institute of Biomedical Research, 250 Massachusetts Avenue, Cambridge, MA 02139, USA.

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