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Science  08 Apr 2016:
Vol. 352, Issue 6282, pp. 247
DOI: 10.1126/science.352.6282.247-a

Data Access Software

Aureum data access software helps companies find, manage, mine, and reuse exponentially growing data assets. Researchers can use it as a tool to find previously dark historical data to promote new findings and insights. A fully integrated search service requires reindexing only when a file is changed, not when it is moved. Interoperability with the Hadoop distributed file system (HDFS) and the portable operating system interface (POSIX) empowers users to perform computations on Hadoop or Spark and store data regardless of application, storage type, or location of the original data. This interoperability, combined with permanent pathnames, allows users to "trace back" to original data when a new analysis of the source data is necessary, enabling scientists to draw correct conclusions. Aureum's dynamically expandable data space ensures that pathnames never change. This benefits researchers looking for datasets years or even decades later, even after dozens of tech refresh cycles.

Chromatin Immunoprecipitation Kit

Native chromatin immunoprecipitation (N-ChIP) is an alternative to traditional cross-linked ChIP (X-ChIP), which removes the need for fixing cells with formaldehyde prior to extraction. As a consequence, the cells remain in a more natural "native state." The new Chromatrap N-ChIP kit provides a quicker, easier, and more efficient way of performing N-ChIP assays (Patent No. GB2482209). It uses discs of an inert, porous polymer to which Protein A or Protein G has been covalently attached to maximize the capture efficiency of the target chromatin/antibody complex. Unlike other approaches, the Chromatrap N-ChIP kit eliminates using agarose or magnetic beads, resulting in more sample being retained during the extraction process. In addition, Chromatrap N-ChIP technology increases the affinity of antibody binding to antigens on native chromatin, as peptides are more accessible. As a result, the Chromatrap N-ChIP kit sets a new standard for enriching transcription factors from native chromatin.

High-Throughput Evaporation

Series 3 HT evaporators are compact in design and offer a very high capacity for a wide range of sample formats including microplates, vials, and fraction collection tubes. The high-throughput (HT) design of the Series 3 HT evaporator allows up to 48 shallow-well microplates to be dried down at the same time, while capacity for standard 16 mm × 100 mm fraction collector tubes is an outstanding 288 tubes per run. To increase throughput further, several Series 3 HT evaporators may be run in parallel on an Infinity trolley system, which is designed to accommodate multiple Genevac evaporators in the optimum configuration to minimize the footprint of the supported system. Available in HT-12 and HT-6 configurations, Series 3 HT evaporators are the system of choice for high-throughput sample drying because of their high sample capacity, their unique technology that eliminates cross contamination caused by sample bumping, and automated temperature and pressure monitoring that prevents sample degradation.

qPCR/RT-qPCR Kits

More than 200 kits are offered under the ViPrimePLUS qPCR/RT-qPCR group. All of these kits have been developed with high specific genome detection capability. They are fast, easy to use, and have high sensitivity. The ViPrimePLUS qPCR/RT-qPCR Master Mix kits are advanced formulations designed for compatibility with most real-time polymerase chain reaction (PCR) platforms on the market, with high sensitivity towards low-abundance transcripts. Vivantis is a research-based biotechnology company that was founded in 2002. The company specializes in the production of restriction enzymes, DNA extraction kits, DNA amplification reagents, and other related products for molecular biology research.

Analyte Identification and Quantitation

Scientists performing nano liquid chromatography-mass spectrometry (LC-MS) analyses who seek accurate quantitation and analyte identification can now use a system designed to deliver higher retention time precision and ease of use. The latest version of the UltiMate 3000 RSLCnano UHPLC system combines higher nano LC performance with versatility and ease of use. New ProFlow technology increases retention time precision, resulting in high-quality data with accurate quantitation. Additionally, the system offers reduced time and simplified system operation so that researchers can focus more time on data acquisition and analysis. The UltiMate 3000 RSLCnano offers a wide flow range (nano-to-micro flow rates) in ultra-high-performance liquid chromatography (UHPLC) mode as well as an additional micro-to-analytical flow ternary gradient pump for increased versatility. As a result, almost any low-flow workflow can benefit from this system. Dedicated kits are available for many standard and advanced (e.g., 2D) workflows.

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  • Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

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