Metabolic Imprinting

Inheriting Mom's exercise regime

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Science  22 Apr 2016:
Vol. 352, Issue 6284, pp. 425-426
DOI: 10.1126/science.352.6284.425-c

Moms can pass on their propensity to exercise, at least in mice.

PHOTO: © WAVEBREAK MEDIA LTD. /ALAMY STOCK PHOTO

Mounting evidence suggests that parents pass on more than just their DNA to their offspring. In the latest example, Eclarinal et al. examined the effect of exercise during pregnancy on the voluntary physical activity of the offspring in adulthood. The researchers kept pregnant mice in cages with either an unlocked or locked running wheel and monitored their physical activity. Daughters of moms who could exercise showed increased activity and voluntary exercise some 60 to 300 days after they were born. The findings complement others showing that in mice, the maternal environment can influence the metabolic status of progeny, and in humans, maternal exercise benefits offspring.

FASEB J. 10.1096/fj.201500018R (2016).

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