PerspectiveCell Metabolism

The resurgence of NAD+

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Science  17 Jun 2016:
Vol. 352, Issue 6292, pp. 1396-1397
DOI: 10.1126/science.aag1718

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Interventions that can slow mammalian aging have been rare. On pages 1436 and 1474 of this issue, Zhang et al. (1) and Cambronne et al. (2), respectively, highlight nicotinamide adenine dinucleotide (NAD+) as a major intervention point to slow or ameliorate phenotypes of aging.