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Identification of an NKX3.1-G9a-UTY transcriptional regulatory network that controls prostate differentiation

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Science  24 Jun 2016:
Vol. 352, Issue 6293, pp. 1576-1580
DOI: 10.1126/science.aad9512

Article Information

vol. 352 no. 6293 1576-1580

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History: 
  • Received for publication November 29, 2015
  • Accepted for publication May 27, 2016

Author Information

  1. Aditya Dutta1,*,
  2. Clémentine Le Magnen1,*,
  3. Antonina Mitrofanova2,,
  4. Xuesong Ouyang3,,
  5. Andrea Califano4,
  6. Cory Abate-Shen5,§
  1. 1Departments of Medicine and Urology, Institute of Cancer Genetics, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY 10032, USA.
  2. 2Department of Systems Biology, Columbia University Medical Center, New York, NY 10032, USA.
  3. 3Department of Urology, Columbia University Medical Center, New York, NY 10032, USA.
  4. 4Departments of Systems Biology, Biomedical Informatics, and Biochemistry and Molecular Biophysics, Center for Computational Biology and Bioinformatics, Institute of Cancer Genetics, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY 10032, USA.
  5. 5Departments of Urology, Medicine, Systems Biology, and Pathology and Cell Biology, Institute of Cancer Genetics, Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, NY 10032, USA.
  1. §Corresponding author. Email: cabateshen{at}columbia.edu
  1. * These authors contributed equally to this work.

  • Present address: Department of Health Informatics, Rutgers, The State University of New Jersey, 65 Bergen Street, Room 350B, Newark, NJ 07101, USA.

  • Present address: Crown Bioscience Inc., 6 West Beijing Road, Taicang, Jiangsu 215400, China.

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