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Science  01 Jul 2016:
Vol. 353, Issue 6294, pp. 87
DOI: 10.1126/science.353.6294.87

Automated Colony Counter

The new aCOLyte 3 HD is a next-generation, automated colony counter for microbiologists who demand a sensitive, affordable system to quickly and accurately count colonies of all sizes and colors. The aCOLyte 3 HD features a high-resolution megapixel charge-coupled device (CCD) camera for accurate detection of different colored microbial colonies as small as 0.1 mm in diameter. The system's powerful software can analyze pour, spread, and spiral plates of up to 90-mm diameter, generating stunning full-color plate images and precise counts in seconds. The results can be directly transferred to Excel and other software packages to avoid keying and scanning errors, guaranteeing accurate GLP-compliant reporting and full data traceability every time. The aCOLyte 3 HD is ideal because it can be easily connected via USB port to a microbiologist's own tablet, laptop, desktop PC, or a computer purchased with the system.

Sequel System

The new Sequel System is based on Pacific Biosciences' proven single molecule, real-time (SMRT) technology and contains 1 million zero-mode waveguides per SMRT Cell. The Sequel System is ideal for projects such as rapid and cost-effective generation of high-quality, whole-genome de novo assemblies. It can provide characterization of a wide variety of genomic variation types, including those in complex regions not accessible with short-read or synthetic long-range sequencing technologies, while simultaneously revealing epigenetic information.

Ion Chromatography System

The Dionex Integrion High-Pressure Ion Chromatography (HPIC) system is intuitive, easy to use, and capable of addressing challenging laboratory workflows. The Dionex Integrion HPIC system delivers features previously available only on Thermo Scientific high-end systems, including high-pressure capability and optional electrochemical detection. With a simple, logical, flow-based plumbing layout and integrated performance features, including whole-system smart monitoring, the Dionex offers fast run times in a robust and reliable system. Additional features may include easy-to-install ion chromatography polyetheretherketone viper fittings, as well as a detachable tablet, a consumables device monitor, a thermally regulated detector compartment, and the Thermo Scientific Dionex Chromeleon Chromatography Data System.

Multimode Reader

The Spark 20M multimode microplate reader offers tailor-made solutions to suit virtually any drug discovery or advanced life science research application. This freely configurable system gives researchers access to new techniques and features intended to enhance and streamline biochemical and cell-based workflows. At the heart of the instrument are Spark's unique Fusion Optics and a powerful, high-frequency xenon flash lamp, which can be combined with any choice of high-performance detection modules to ensure a perfect workflow match. Options include an enhanced fluorescence module designed to improve sensitivity and increase the speed of high-throughput screening, and the newly developed Te-Cool cooling module that uniquely allows the measurement chamber temperature to be set below the ambient room temperature for more accurate and reliable results. The Spark 20M's cell-handling capabilities have also been extended, with a new automated cell-imaging and confluence measurement feature.

Ultrasound Research System

The RK-50 is a stand-alone, versatile, preclinical system that enables scientists to take advantage of the many powerful applications of focused ultrasound (FUS). Through the use of standard stereotaxic targeting methods facilitated by image-guided treatment-planning software, the RK-50 can deliver precise doses of FUS through an intact skull to small structures in the rodent brain. The RK-50 is particularly well suited for blood-brain barrier disruption. This technology represents a noninvasive alternative to stereotaxic injections that has been used to deliver a variety of agents to the brain, including chemotherapeutics, small interfering RNA amyloid antibodies, genes, contrast agents, nanoparticles, and stem cells.

Waveform Generator

A new ultra-high frequency arbitrary waveform generator (UHF-AWG) enables fast and intuitive waveform programming with sequence branching for quantum computing, nuclear magnetic resonance spectroscopy, and mixed-signal device testing customers. The UHF-AWG is a dual-channel, 600-MHz AWG with 128-megasample waveform memory per channel and 1.8-gigasample-per-second temporal and 14-bit vertical resolution. Integrated detection options include a pulse counter, multiple demodulators, an oscilloscope, and a boxcar averager. Signal generation and detection merged into a single instrument minimizes feedback times and experimental setup. The AWG is fully integrated into the LabOne instrument control software that provides high-level AWG commands. Pulse sequences and waveforms can be easily defined and adjusted. The UHF-AWG features standard waveform playback and amplitude modulation. In amplitude modulation mode, each AWG channel shapes one of up to eight internally generated sine wave signals and does not require uploading the entire waveform. The UHF-AWG has easy upgrade paths.

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  • Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are featured in this space. Emphasis is given to purpose, chief characteristics, and availabilty of products and materials. Endorsement by Science or AAAS of any products or materials mentioned is not implied. Additional information may be obtained from the manufacturer or supplier.

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