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Mitochondrial endonuclease G mediates breakdown of paternal mitochondria upon fertilization

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Science  22 Jul 2016:
Vol. 353, Issue 6297, pp. 394-399
DOI: 10.1126/science.aaf4777

Article Information

vol. 353 no. 6297 394-399

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History: 
  • Received for publication February 14, 2016
  • Accepted for publication June 15, 2016

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Author Information

  1. Qinghua Zhou1,*,,
  2. Haimin Li1,*,
  3. Hanzeng Li1,2,*,
  4. Akihisa Nakagawa1,
  5. Jason L. J. Lin3,
  6. Eui-Seung Lee1,
  7. Brian L. Harry1,4,
  8. Riley Robert Skeen-Gaar1,
  9. Yuji Suehiro5,
  10. Donna William6,
  11. Shohei Mitani5,
  12. Hanna S. Yuan3,
  13. Byung-Ho Kang7,,
  14. Ding Xue1,
  1. 1Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO 80309, USA.
  2. 2Department of Chemistry and Biochemistry, University of Colorado, Boulder, CO 80309, USA.
  3. 3Institute of Molecular Biology, Academia Sinica, Taipei 11529, Taiwan.
  4. 4Medical Scientist Training Program, University of Colorado, Aurora, CO 80045, USA.
  5. 5Department of Physiology, Tokyo Women’s Medical University, School of Medicine and CREST, Japan Science and Technology Agency, Tokyo 162-8666, Japan.
  6. 6Department of Microbiology and Cell Science, University of Florida, Gainesville, FL 32611, USA.
  7. 7School of Life Sciences, Centre for Cell and Developmental Biology and State Key Laboratory of Agrobiotechnology, Chinese University of Hong Kong, Hong Kong, China.
  1. Corresponding author. Email: ding.xue{at}colorado.edu (D.X.); bkang{at}cuhk.edu.hk (B.-H.K.)
  1. * These authors contributed equally to this work.

  • Present address: First Affiliated Hospital, Biomedical Translational Research Institute, Jinan University, Guangzhou 510630, China.

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