Feature

A reporter does CRISPR

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Science  04 Nov 2016:
Vol. 354, Issue 6312, pp. 541
DOI: 10.1126/science.354.6312.541

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Summary

The details of CRISPR, the new genome-editing tool, baffled Science magazine reporter Jon Cohen so he decided to run his own experiment with the help of scientist Roland Wagner at the Sanford Burnham Prebys Medical Discovery Institute in San Diego, California. Cohen had heard that “any idiot” could do CRISPR, so his experiment tests this hypothesis. As he hoped, conducting a CRISPR experiment with his own hands clarified how it actually works and what the challenges are to properly carrying out the cutting of DNA. But to find out whether any idiot can do it, read the story.