PerspectiveEpidemiology

Leprosy in red squirrels

See allHide authors and affiliations

Science  11 Nov 2016:
Vol. 354, Issue 6313, pp. 702-703
DOI: 10.1126/science.aal0145

You are currently viewing the summary.

View Full Text

Log in to view the full text

Log in through your institution

Log in through your institution

Summary

In 1873, the Norwegian doctor Armauer Hansen helped to lay the foundations of modern microbiology when he discovered that leprosy was an infectious disease, not an inherited condition. However, his attempts to cultivate the rod-shaped bacilli that he had observed in microscopic studies of tissues from leprosy patients were unsuccessful, emphasizing the unique growth requirements of these bacilli. Even today, Mycobacterium leprae, the causative organism of leprosy, cannot be grown on culture media, and many questions remain about its mode of transmission and epidemiology (1). The unexpected identification of red squirrels (Sciurus vulgaris) as an extant animal reservoir of leprosy bacilli by Avanzi et al. (2) on page 744 of this issue elucidates the host conditions that may allow leprosy bacilli to multiply and cause disease.