This Week in ScienceDRUG DELIVERY

Toward malaria eradication

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Science  18 Nov 2016:
Vol. 354, Issue 6314, pp. 843-844
DOI: 10.1126/science.354.6314.843-h

Even though we know how to prevent malaria, we have failed to eliminate this damaging disease. Bellinger et al. designed an easy-to-administer device that provides long-lasting delivery of an antimalarial drug. A star-shaped, drug-containing material is packaged into a capsule. When swallowed, the capsule dissolves in the stomach and the star unfolds, assuming a shape that cannot pass further down the intestine. The star delivers the anti-malarial drug for weeks, but eventually falls apart and passes harmlessly out of the body.

Sci. Transl. Med. 8, 365ra157 (2016).

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