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Tissue damage and senescence provide critical signals for cellular reprogramming in vivo

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Science  25 Nov 2016:
Vol. 354, Issue 6315, aaf4445
DOI: 10.1126/science.aaf4445

Article Information

vol. 354 no. 6315

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History: 
  • Received for publication February 9, 2016
  • Resubmitted July 1, 2016
  • Accepted for publication October 6, 2016

Author Information

  1. Lluc Mosteiro1,
  2. Cristina Pantoja1,*,
  3. Noelia Alcazar1,*,
  4. Rosa M. Marión2,
  5. Dafni Chondronasiou1,
  6. Miguel Rovira1,
  7. Pablo J. Fernandez-Marcos1,3,
  8. Maribel Muñoz-Martin1,
  9. Carmen Blanco-Aparicio4,
  10. Joaquin Pastor4,
  11. Gonzalo Gómez-López5,
  12. Alba De Martino6,
  13. Maria A. Blasco2,
  14. María Abad1,7,
  15. Manuel Serrano1,
  1. 1Tumor Suppression Group, Spanish National Cancer Research Centre (CNIO), Madrid E28029, Spain.
  2. 2Telomeres and Telomerase Group, CNIO, Madrid E28029, Spain.
  3. 3Laboratory of Bioactive Products and Metabolic Syndrome, Madrid Institute for Advanced Studies (IMDEA) in Food, CEI UAM+CSIC, Madrid E28049, Spain.
  4. 4Experimental Therapeutics Programme, CNIO, Madrid E28029, Spain.
  5. 5Bioinformatics Unit, CNIO, Madrid E28029, Spain.
  6. 6Histopathology Unit, CNIO, Madrid E28029, Spain.
  7. 7Cell Plasticity and Cancer Group, Vall d’Hebron Institute of Oncology (VHIO), Barcelona E08035, Spain.
  1. Corresponding author. Email: mserrano{at}cnio.es
  1. * These authors contributed equally to this work.

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