Business Office Feature

Editing the editor: Genome editing gets a makeover with CRISPR 2.0

See allHide authors and affiliations

Science  13 Jan 2017:
Vol. 355, Issue 6321, pp. 210
DOI: 10.1126/science.355.6321.210-c


Applications of the genome editing system CRISPR are appearing at a furious pace, and gathering momentum toward therapeutic use in human cells. Indeed, Chinese scientists recently began a human clinical trial using CRISPR-edited cells to fight lung cancer, and U.S. clinical trials are slated to begin in 2017. But leading up to this exciting milestone, researchers performed some editing on the CRISPR system itself. Here's a look at some recent CRISPR upgrades that are helping to move it closer toward use in clinics.