Gene duplication can impart fragility, not robustness, in the yeast protein interaction network

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Science  10 Feb 2017:
Vol. 355, Issue 6325, pp. 630-634
DOI: 10.1126/science.aai7685

Article Information

vol. 355 no. 6325 630-634

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  • Received for publication September 13, 2016
  • Accepted for publication January 13, 2017

Author Information

  1. Guillaume Diss1,2,3,4,5,
  2. Isabelle Gagnon-Arsenault1,2,3,
  3. Anne-Marie Dion-Coté1,2,3,*,
  4. Hélène Vignaud1,2,3,
  5. Diana I. Ascencio1,2,3,6,
  6. Caroline M. Berger1,2,3,
  7. Christian R. Landry1,2,3,
  1. 1Département de Biologie, Université Laval, Québec, QC, Canada.
  2. 2The Quebec Network for Research on Protein Function, Engineering, and Applications, Université Laval, Québec, QC, Canada.
  3. 3Institut de Biologie Intégrative et des Systèmes, Université Laval, Québec, QC, Canada.
  4. 4EMBL/CRG Systems Biology Research Unit, Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology (BIST), Doctor Aiguader 88, 08003 Barcelona, Spain.
  5. 5Universitat Pompeu Fabra (UPF), 08003 Barcelona, Spain.
  6. 6Laboratorio Nacional de Genómica para la Biodiversidad (LANGEBIO), Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Irapuato, Guanajuato, Mexico.
  1. Corresponding author. Email: christian.landry{at}
  • * Present address: Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853-2703, USA.


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