Report

Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice

+ See all authors and affiliations

Science  17 Feb 2017:
Vol. 355, Issue 6326, pp. 756-760
DOI: 10.1126/science.aal0092

You are currently viewing the editor's summary.

View Full Text

Vitamin B3 protects mice from glaucoma

Glaucoma is the most common cause of age-related blindness in the United States. There is currently no cure, and once vision is lost, the condition is irreversible. Williams et al. now report that vitamin B3 (also known as niacin) prevents eye degeneration in glaucoma-prone mice (see the Perspective by Crowston and Trounce). Supplementing the diets of young mice with vitamin B3 averted early signs of glaucoma. Vitamin B3 also halted further glaucoma development in aged mice that already showed signs of the disease. Thus, healthy intake of vitamin B3 may protect eyesight.

Science, this issue p. 756; see also p. 688