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Vitamin B3 modulates mitochondrial vulnerability and prevents glaucoma in aged mice

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Science  17 Feb 2017:
Vol. 355, Issue 6326, pp. 756-760
DOI: 10.1126/science.aal0092

Article Information

vol. 355 no. 6326 756-760

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History: 
  • Received for publication September 29, 2016
  • Accepted for publication December 23, 2016

Author Information

  1. Pete A. Williams1,
  2. Jeffrey M. Harder1,
  3. Nicole E. Foxworth1,
  4. Kelly E. Cochran1,
  5. Vivek M. Philip1,
  6. Vittorio Porciatti2,
  7. Oliver Smithies3,
  8. Simon W. M. John1,4,5,*
  1. 1The Jackson Laboratory, Bar Harbor, ME 04609, USA.
  2. 2Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
  3. 3Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.
  4. 4Department of Ophthalmology, Tufts University of Medicine, Boston, MA 02111, USA.
  5. 5The Howard Hughes Medical Institute, Bar Harbor, ME 04609, USA.
  1. *Corresponding author. Email: simon.john{at}jax.org

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