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A nontoxic pain killer designed by modeling of pathological receptor conformations

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Science  03 Mar 2017:
Vol. 355, Issue 6328, pp. 966-969
DOI: 10.1126/science.aai8636

Article Information

vol. 355 no. 6328 966-969

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History: 
  • Received for publication August 24, 2016
  • Accepted for publication January 30, 2017

Author Information

  1. V. Spahn1,,
  2. G. Del Vecchio1,,
  3. D. Labuz1,
  4. A. Rodriguez-Gaztelumendi1,
  5. N. Massaly1,*,
  6. J. Temp1,
  7. V. Durmaz2,
  8. P. Sabri2,
  9. M. Reidelbach2,
  10. H. Machelska1,
  11. M. Weber2,,
  12. C. Stein1,,§
  1. 1Department of Anesthesiology and Critical Care Medicine, Charité-Universitätsmedizin Berlin Campus Benjamin Franklin, Freie Universität Berlin, Hindenburgdamm 30, Berlin 12203, Germany.
  2. 2Computational Molecular Design, Zuse-Institut Berlin, Takustrasse 7, Berlin, 14195, Germany.
  1. §Corresponding author. E-mail: christoph.stein{at}charite.de
  1. These authors contributed equally to this work.

  2. These authors contributed equally to this work.

  • * Present address: Washington University Pain Center, Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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