Research Article

Design of a synthetic yeast genome

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Science  10 Mar 2017:
Vol. 355, Issue 6329, pp. 1040-1044
DOI: 10.1126/science.aaf4557

Article Information

vol. 355 no. 6329 1040-1044

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History: 
  • Received for publication February 15, 2016
  • Accepted for publication January 26, 2017

Author Information

  1. Sarah M. Richardson1,2,*,,
  2. Leslie A. Mitchell2,3,,
  3. Giovanni Stracquadanio1,2,4,,
  4. Kun Yang1,2,,
  5. Jessica S. Dymond2,,
  6. James E. DiCarlo2,,
  7. Dongwon Lee1,§,
  8. Cheng Lai Victor Huang2,
  9. Srinivasan Chandrasegaran5,
  10. Yizhi Cai2,6,
  11. Jef D. Boeke2,3,#,
  12. Joel S. Bader1,2,#
  1. 1Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205, USA.
  2. 2High Throughput Biology Center, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  3. 3Institute for Systems Genetics and Department of Biochemistry and Molecular Pharmacology, New York University Langone Medical Center, New York, NY 10016, USA.
  4. 4School of Computer Science and Electronic Engineering, University of Essex, Wivenhoe Park, Colchester CO4 3SQ, UK.
  5. 5Department of Environmental Health Science, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
  6. 6University of Edinburgh, School of Biological Sciences, University of Edinburgh, Edinburgh EH9 3BF, UK.
  1. #Corresponding author. Email: jef.boeke{at}nyumc.org (J.D.B.); joel.bader{at}jhu.edu (J.S.B.)
  1. These authors contributed equally to this work.

  • * Present address: Ignition Genomics, 12240 Roundwood Road, Unit 703, Timonium, MD 21093, USA.

  • Present address: Research and Exploratory Development Department, Biological Sciences, Johns Hopkins University Applied Physics Laboratory, 11100 Johns Hopkins Road, Mail Stop 21-N352, Laurel, MD 20723, USA.

  • Present address: Department of Ophthalmology, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA.

  • § Present address: McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.

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