DRUG ADDICTION

A vaccine for heroin addiction?

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Science  30 Jun 2017:
Vol. 356, Issue 6345, pp. 1347-1348
DOI: 10.1126/science.356.6345.1347-f

Addiction to opiate drugs has become a worldwide public health epidemic. Bremer et al. sought to test whether a vaccination approach might be a way to combat heroin addiction. They designed a vaccine that contained part of the heroin molecule, which trained the immune system in monkeys to produce antibodies against heroin. The vaccine was able to neutralize heroin and prevent the heroin high feeling for up to 8 months. Antiheroin immunity continued to improve over time with the administration of booster shots. The researchers next aim to test the vaccine in human trials.

J. Am. Chem. Soc. 10.1021/jacs.7b03334 (2017).

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