Contents
Vol 357, Issue 6347
Special Issue
Emerging Infectious Diseases
Introduction to special issue
EMERGING INFECTIOUS DISEASES
Reviews
Contents
This Week in Science
Editorial
Editors' Choice
Products & Materials
- New Products
A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.
In Brief
In Depth
- Labmade smallpox is possible, study shows
Reconstitution of horsepox virus from mail-order DNA reignites synthetic biology debate
- Trump's science shop is small and waiting for leadership
White House office has so far played little role in policy
- CubeSat networks hasten shift to commercial weather data
Two companies hope to sell atmospheric data to NOAA
- A trans-Atlantic transparency gap on animal experiments
As institutions in the United Kingdom and elsewhere publicize their research, many U.S. universities stay quiet
- A push for low-carbon fuels pays off in California
But new EPA rule would cut federal support for advanced biofuels like biodiesel
Feature
- Surviving the cure
A stem cell transplant helped beat back a young doctor's cancer. Now, it's assaulting his body
Working Life
Letters
Books et al.
- The Sun spotters
An 1878 eclipse offered American scientists the chance to prove their scientific chops. Did they deliver?
- The elegant law that governs us all
A physicist probes a phenomenon seen in cells, cities, and almost everything in between
Policy Forum
- When early adopters don't adopt
How do bitcoin early adopters seed the adoption S curve?
Perspectives
- A raven's memories are for the future
Ravens can plan for expected future events based on past experiences
- The importance of being modular
An experiment proves the value of modularity in complex systems under perturbation
- Immunology taught by rats
A rodent model of hepatitis C virus infection should guide therapeutics and vaccines
- Of sizzling steaks and DNA repair
A pathway protects cells from mutations caused by sugar-derived aldehydes
- Plasmonic imaging is gaining momentum
Terahertz nanospectroscopy reveals many-body interactions in graphene
- How do miniproteins fold?
A high-throughput study yields libraries of miniproteins that help to explain how proteins are stabilized
Research Articles
- History of winning remodels thalamo-PFC circuit to reinforce social dominance
Synaptic plasticity of a thalamo–prefrontal cortex circuit underlies the winner effect and transfer of social dominance in mice.
- Global analysis of protein folding using massively parallel design, synthesis, and testing
Thousands of computationally designed proteins quantify the global determinants of miniprotein stability.
- Snap deconvolution: An informatics approach to high-throughput discovery of catalytic reactions
Parallel screening of three pools of similar reagents that differ in mass facilitates rapid discovery of coupling reactions.
Reports
- High-temperature quantum oscillations caused by recurring Bloch states in graphene superlattices
Magnetotransport in graphene–hexagonal boron nitride heterostructures exhibits robust oscillations.
- Reconciling solar and stellar magnetic cycles with nonlinear dynamo simulations
Simulations explain why the Sun’s activity cycle seems not to match that of other solar-type stars.
- Tuning quantum nonlocal effects in graphene plasmonics
Tunable plasmons are used to probe the quantum properties of an electronic system.
- All-oxide–based synthetic antiferromagnets exhibiting layer-resolved magnetization reversal
Superlattices made of layers of ferromagnetic La2/3Ca1/3MnO3 and insulating CaRu1/2Ti1/2O3 show antiferromagnetic coupling.
- Control and local measurement of the spin chemical potential in a magnetic insulator
Nanometer spatial resolution measurement is achieved using nitrogen-vacancy centers in diamond.
- Effects of network modularity on the spread of perturbation impact in experimental metapopulations
Networks of springtail (Folsomia candida) microarthropods are more robust to perturbation when organized in modules.
- Ravens parallel great apes in flexible planning for tool-use and bartering
Ravens can plan for the future.
- Mouse models of acute and chronic hepacivirus infection
A mouse model may provide mechanistic insights into the immune response to hepatitis C virus infection.
- Guanine glycation repair by DJ-1/Park7 and its bacterial homologs
A DNA repair system acts specifically on bases damaged by reaction with by-products of sugar metabolism in the cell.
- Germ line–inherited H3K27me3 restricts enhancer function during maternal-to-zygotic transition
Inherited repressive epigenetic information controls transcriptional output in offspring.
Technical Comments
About The Cover

COVER A groundskeeper sprays pesticide to control mosquitoes in Miami, Florida, in 2016. Zika virus is spread by the ubiquitous Aedes aegypti mosquito. This flavivirus has caused a huge outbreak of infection across South America, where it has been associated with neurological abnormalities in newborn children. The virus has spread north, and cases of infection have been detected in the United States. For more on anticipating infectious disease outbreaks, see page 144.
Photo: © Gaston De Cardenas/Miami Herald/TNS via Getty Images