Technical Comments

Comment on “Molecular and neural basis of contagious itch behavior in mice”

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Science  14 Jul 2017:
Vol. 357, Issue 6347, eaan4749
DOI: 10.1126/science.aan4749

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Yu et al. (Reports, 10 March 2017, p. 1072) state that contagious itch occurs in mice based on imitative scratching in normal mice observing excessive scratching in genetically modified demonstrator mice. However, despite employing multiple behavioral analysis approaches, we were unable to extend these findings to normal mice observing the well-established histamine model of acute itch in demonstrator mice.

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