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Single-cell methylomes identify neuronal subtypes and regulatory elements in mammalian cortex

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Science  11 Aug 2017:
Vol. 357, Issue 6351, pp. 600-604
DOI: 10.1126/science.aan3351

Article Information

vol. 357 no. 6351 600-604

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History: 
  • Received for publication March 31, 2017
  • Accepted for publication July 13, 2017

Author Information

  1. Chongyuan Luo1,2,*,
  2. Christopher L. Keown3,*,
  3. Laurie Kurihara4,
  4. Jingtian Zhou1,5,
  5. Yupeng He1,5,
  6. Junhao Li3,
  7. Rosa Castanon1,
  8. Jacinta Lucero6,
  9. Joseph R. Nery1,
  10. Justin P. Sandoval1,
  11. Brian Bui6,
  12. Terrence J. Sejnowski2,6,7,
  13. Timothy T. Harkins4,
  14. Eran A. Mukamel3,,
  15. M. Margarita Behrens6,,
  16. Joseph R. Ecker1,2,
  1. 1Genomic Analysis Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  2. 2Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  3. 3Department of Cognitive Science, University of California, San Diego, La Jolla, CA 92037, USA.
  4. 4Swift Biosciences Inc., 58 Parkland Plaza, Suite 100, Ann Arbor, MI 48103, USA.
  5. 5Bioinformatics and Systems Biology Program, University of California, San Diego, La Jolla, CA 92093, USA.
  6. 6Computational Neurobiology Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
  7. 7Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA.
  1. Corresponding author. Email: ecker{at}salk.edu (J.R.E.); mbehrens{at}salk.edu (M.M.B.); emukamel{at}ucsd.edu (E.A.M.)
  1. * These authors contributed equally to this work.

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