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Paneth cells secrete lysozyme via secretory autophagy during bacterial infection of the intestine

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Science  08 Sep 2017:
Vol. 357, Issue 6355, pp. 1047-1052
DOI: 10.1126/science.aal4677

Article Information

vol. 357 no. 6355 1047-1052

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History: 
  • Received for publication November 25, 2016
  • Resubmitted April 12, 2017
  • Accepted for publication July 14, 2017

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Author Information

  1. Shai Bel1,
  2. Mihir Pendse1,
  3. Yuhao Wang1,
  4. Yun Li1,
  5. Kelly A. Ruhn1,
  6. Brian Hassell1,
  7. Tess Leal1,
  8. Sebastian E. Winter2,
  9. Ramnik J. Xavier3,4,5,
  10. Lora V. Hooper1,6,*
  1. 1Department of Immunology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  2. 2Department of Microbiology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  3. 3Broad Institute, Cambridge, MA 02142, USA.
  4. 4Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA 02114, USA.
  5. 5Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02142, USA.
  6. 6The Howard Hughes Medical Institute, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
  1. *Corresponding author. Email: lora.hooper{at}utsouthwestern.edu

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Dec 201725836161