Contents
Vol 357, Issue 6356
Contents
This Week in Science
Editorial
Editors' Choice
Multimedia
Products & Materials
- New Products
A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.
In Brief
In Depth
- Bot-hunters eye mischief in German election
Fake social media profiles are proliferating, but their potency is unclear.
- NIH quietly shelves gun research program
Agency says it might still renew funding opportunity, which answered Obama call after school shooting.
- ‘Supergenes’ drive evolution
Flipped DNA speeds the emergence of new sets of traits.
- Unusual quake rattles Mexico
Magnitude-8.2 earthquake may have relieved stress in Tehuantepec gap after more than 100 years of quiet.
- Pay up or retract? Drug survey spurs conflict
Researchers' zealous effort to protect intellectual property has included legal threats.
- Papua New Guinea's genetic diversity withstood farming
Island somehow resisted homogenization seen elsewhere.
- PETA targets early-career wildlife researcher
Critics say animal rights organization is trying to intimidate vulnerable scientists.
Feature
- Keeping the faith
In the face of persistent critics, paleontologist Mary Schweitzer pursues evidence of dinosaur proteins.
Working Life
Letters
Books et al.
- Pairing off
A boom in mate choice research prompts a comprehensive look at the state of the field
- Darwin, the crowdsourcer
Friends and family helped the naturalist form his famous theory
Policy Forum
- Without inclusion, diversity initiatives may not be enough
Focus on minority experiences in STEM, not just numbers
Perspectives
- Neurons that drive and quench thirst
Median preoptic neurons modulate water intake and the urge to drink
- The refrigerant is also the pump
An electrocaloric polymer cooler efficiently pumps heat from cold to hot reservoirs
- DNA robots sort as they walk
Multiple DNA robots perform parallel tasks on a self-assembled DNA origami surface
- Crystal-clear memories of a bacterium
Structures of the CRISPR memorization complex in bacteria reveal new mechanistic details
- Scattering neutrinos caught in the act
Neutrino experiment finds new tool to search for physics beyond the standard model
- Microbial mass movements
Wastewater, tourism, and trade are moving microbes around the globe at an unprecedented scale
Review
Research Articles
- A cargo-sorting DNA robot
A single-stranded DNA with modular function domains undergoes a random walk and sorts two molecular cargoes.
- Structures of the CRISPR genome integration complex
The CRISPR integration complex relies on structural features of DNA to achieve site-selective CRISPR array expansion.
Reports
- Biological fabrication of cellulose fibers with tailored properties
Biological incorporation of functional molecules into cotton fibers adds magnetic or optical properties.
- Observation of coherent elastic neutrino-nucleus scattering
A 14.6-kilogram sodium-doped CsI scintillator is used to detect a neutrino scattering process with a 6.7σ confidence level.
- DNA sequence–directed shape change of photopatterned hydrogels via high-degree swelling
DNA molecules direct the swelling of cross-linked hydrogels with shape changes in response to different biomolecular signals.
- Highly efficient electrocaloric cooling with electrostatic actuation
A flexible and lightweight device uses an electrocaloric polymer film to provide exceptional cooling power.
- Soft x-ray excitonics
Consecutive attosecond pulses reveal the dynamics of excitons ensuing from core-electron excitation in silica.
- Fabrication of fillable microparticles and other complex 3D microstructures
Technology used for computer chip manufacturing is combined with soft lithography to produce small polymeric structures.
- Distinct phases of Polycomb silencing to hold epigenetic memory of cold in Arabidopsis
A multifactorial strategy establishes and maintains repressive chromatin marks in plants in response to environmental signals.
- DNA replication–coupled histone modification maintains Polycomb gene silencing in plants
A multifactorial strategy establishes and maintains repressive chromatin marks in plants in response to environmental signals.
- Thirst-associated preoptic neurons encode an aversive motivational drive
A cell type in the median preoptic nucleus integrates water intake over time and controls thirst behavior in mice.
- Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine
In model systems, bacteria present in human pancreatic tumors confer resistance to the anticancer drug gemcitabine.
- A Neolithic expansion, but strong genetic structure, in the independent history of New Guinea
The population structure in Papua New Guinea reflects a Neolithic transition with high present-day genetic differentiation.
Technical Comments
From the AAAS Office of Publishing and Member Services
About The Cover

COVER Two-kilogram prototype of a 14.6-kilogram cesium iodide crystal used for coherent neutrino detection. The scintillator is encapsulated in ultrapure electroformed copper developed at Pacific Northwest National Laboratory. Ancient, radioisotope-free lead recovered from a Spanish galleon is used to block radioactive emissions from electronic components above the photomultiplier. See pages 1098 and 1123. For more on the process behind the cover image, see http://scim.ag/2xf2q6X.
Photo: Jean Lachat/University of Chicago