Biomaterials

Healing powers of dressing well

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Science  10 Nov 2017:
Vol. 358, Issue 6364, pp. 759-760
DOI: 10.1126/science.358.6364.759-g

Simple dressings, such as bandages, are used to protect against wound infection but can also be enhanced to actively promote wound healing. Critical factors are the permeation of oxygen and maintaining the right level of moisture. On the flip side, high concentrations of hydrogen peroxide can delay healing by preventing the formation of connective tissue. Hu et al. show that hematite nanoparticles, which have shown enzymatic-like activity for the conversion of peroxide into water and oxygen, can be added to poly(vinyl alcohol) membranes made from electrospun fibers. The membranes, cross-linked to retain the particles, were particularly effective at reducing toxic levels of peroxide, allowing fibroblasts to grow unhindered.

ACS Appl. Mater. Interfaces 10.1021/acsami.7b12212 (2017).

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