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Structural basis for methylphosphonate biosynthesis

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Science  08 Dec 2017:
Vol. 358, Issue 6368, pp. 1336-1339
DOI: 10.1126/science.aao3435

Article Information

vol. 358 no. 6368 1336-1339

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History: 
  • Received for publication July 10, 2017
  • Accepted for publication November 6, 2017

Author Information

  1. David A. Born1,2,*,
  2. Emily C. Ulrich3,4,*,
  3. Kou-San Ju4,5,6,
  4. Spencer C. Peck3,4,,
  5. Wilfred A. van der Donk3,4,7,,
  6. Catherine L. Drennan2,8,9,
  1. 1Graduate Program in Biophysics, Harvard University, Cambridge, MA, USA.
  2. 2Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
  3. 3Department of Chemistry, University of Illinois at Urbana–Champaign, Urbana, IL, USA.
  4. 4Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana–Champaign, Urbana, IL, USA.
  5. 5Department of Microbiology, The Ohio State University, Columbus, OH, USA.
  6. 6Division of Medicinal Chemistry and Pharmacognosy, The Ohio State University, Columbus, OH, USA.
  7. 7Howard Hughes Medical Institute, University of Illinois at Urbana–Champaign, Urbana, IL, USA.
  8. 8Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, USA.
  9. 9Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA, USA.
  1. Corresponding author. Email: cdrennan{at}mit.edu (C.L.D.); vddonk{at}illinois.edu (W.A.V.)
  1. * These authors contributed equally to this work.

  • Present address: Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.

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