Research Article

A major chromatin regulator determines resistance of tumor cells to T cell–mediated killing

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Science  16 Feb 2018:
Vol. 359, Issue 6377, pp. 770-775
DOI: 10.1126/science.aao1710

Article Information

vol. 359 no. 6377 770-775

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History: 
  • Received for publication June 21, 2017
  • Resubmitted October 30, 2017
  • Accepted for publication December 14, 2017

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Author Information

  1. Deng Pan1,*,
  2. Aya Kobayashi1,2,*,
  3. Peng Jiang3,*,
  4. Lucas Ferrari de Andrade1,
  5. Rong En Tay1,
  6. Adrienne M. Luoma1,
  7. Daphne Tsoucas3,
  8. Xintao Qiu4,
  9. Klothilda Lim4,
  10. Prakash Rao4,,
  11. Henry W. Long4,
  12. Guo-Cheng Yuan3,
  13. John Doench5,
  14. Myles Brown4,
  15. X. Shirley Liu3,,
  16. Kai W. Wucherpfennig1,6,
  1. 1Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  2. 2Astellas Pharma, Tokyo 103-8411, Japan.
  3. 3Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  4. 4Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
  5. 5Genetic Perturbation Platform, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  6. 6Department of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115, USA.
  1. Corresponding author. Email: kai_wucherpfennig{at}dfci.harvard.edu (K.W.W.); xsliu{at}jimmy.harvard.edu (X.S.L.)
  1. * These authors contributed equally to this work.

  • Present address: Harvard University Office of Technology Development, Cambridge, MA 02138, USA.

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Jan 20181731222173614
Feb 20181426414982791
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