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Comment on “Enhanced water permeability and tunable ion selectivity in subnanometer carbon nanotube porins”

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Science  30 Mar 2018:
Vol. 359, Issue 6383, eaap9173
DOI: 10.1126/science.aap9173

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Abstract

Tunuguntla et al. (Reports, 25 August 2017, p. 792) report that permeation of single-file water occurs faster through carbon nanotubes than through aquaporins. We show that this conclusion violates fundamental thermodynamic laws: Because of its much lower activation energy, aquaporin-mediated water transport must be orders of magnitude faster. Leakage at the nanotube-membrane interface may explain the discrepancy.

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