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Germinal center antibody mutation trajectories are determined by rapid self/foreign discrimination

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Science  13 Apr 2018:
Vol. 360, Issue 6385, pp. 223-226
DOI: 10.1126/science.aao3859

Article Information

vol. 360 no. 6385 223-226

PubMed: 
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History: 
  • Received for publication July 14, 2017
  • Resubmitted December 2, 2017
  • Accepted for publication February 20, 2018

Author Information

  1. Deborah L. Burnett1,2,
  2. David B. Langley1,
  3. Peter Schofield1,2,
  4. Jana R. Hermes1,
  5. Tyani D. Chan1,2,
  6. Jennifer Jackson1,
  7. Katherine Bourne1,
  8. Joanne H. Reed1,
  9. Kate Patterson1,
  10. Benjamin T. Porebski3,
  11. Robert Brink1,2,
  12. Daniel Christ1,2,*,
  13. Christopher C. Goodnow1,2,*
  1. 1Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst, New South Wales 2010, Australia.
  2. 2St. Vincent’s Clinical School, University of New South Wales Sydney, Sydney, Australia.
  3. 3Medical Research Council Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge CB2 OQH, UK.
  1. *Corresponding author. Email: d.christ{at}garvan.org.au (D.C.); c.goodnow{at}garvan.org.au (C.C.G.)

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Apr 2018996611291904
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